There are people out there that will not use poppers correctly. They are uncorking the bottle and sniffing it directly from the source. Another of the different ways to use poppers we have heard of is to put some into a rag or piece of cloth, and then to hold that cloth up to the mouth and nose. Under no circumstances do we suggest that you do this.

Crusty skin lesions: These typically occur around the nose, lips, and other areas exposed to amyl nitrite fumes.Taking the drug in this way can cause irregular and rapid heart rhythms and result in a syndrome called “sudden sniffing death.”

Breathing out through the mask doesn't disrupt the chamber, and you can drop it on the floor and there is no risk of spilling anything anywhere, also no risk of getting any on your skin.

Those that use poppers as a party drug will tend to inhale from the bottle. They may also place some on a rag or piece of cloth. This way they can work out how to sniff poppers on the go. We do not suggest you do this and would advise that you follow our previous directions. To use poppers correctly, always use them in a well-ventilated space and as a room aroma. How to Use Poppers During Sex We always suggest the room you use our powerful room odourisers in be more than 5m x 5m. We would also recommend that it be fully ventilated. If anyone in the room begins to experience dizziness or a headache, all you need to do is replace the cap. Now – this is where things get a little interesting. Science dictates that many men suffer from erectile dysfunction because the blood vessels in the penis don’t get enough oxygen. This means they lose the ability to maintain – or even get – a hard on. The side-effects of poppers, on the other hand, include increased oxygen in the blood. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Cha, H. J., Kim, Y. J., Jeon, S. Y., Kim, Y. H., Shin, J., Yun, J., ... Kim, H. S. (2016, April 21). Neurotoxicity induced by alkyl nitrites: Impairment in learning/memory and motor coordination [Abstract]. Neuroscience Letters, 619, 79–85